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5.3 Direct targeting of MSU crystals to induce inflammatory pathway intervention strategies The acute inflammatory response triggered by MSU crystals primarily involves the activation of the NLRP3 inflammasome and the subsequent release of IL-1

Detection of glutathione in cell culture medium A total 20 l of CAF-, LNCaP- or non-conditioned medium was mixed with 50 l acetone and incubated at 20 C overnight

132 Several phytocompounds, such as Sapidolide A, 47 allicin, 133 and berberine, 134 have been shown to inhibit inflammasome activation and alleviate APAP-induced hepatotoxicity

C.ChalmersJ