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Probenecid is nonselective and inhibits multiple other SLCs and ABC membrane transporters in the kidney, gut, brain, and several other tissues [42]

Consumption of ME-3 boosts the production of a major cellular antioxidant, glutathione

doi: 10.1016/j.celrep.2023.112508, 70 MohammedM

In cystic fibrosis, vitamin C serves as a crucial source of glutathione and aids in maintaining the delicate balance between oxidative stress and antioxidant defense mechanisms within the lungs (94)

In conclusion, both niosomal and conventional TXA/NCA creams are as effective as HQ 4% cream in melasma management through the reduction in mMASI and MI scores and improve patients self-satisfaction and quality of life by a reduction in MelaosQoL score