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GlyNAC supplementation begins to improve age-associated declines within 2-weeks but a longer duration of supplementation is needed for a greater magnitude of improvement

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However, there was a significant increase in the total intensity of reversibly oxidised Cys (the sum of all oxidised peptide intensities) between the ALS and HC groups at the first visit (1.23 fold, P = 0.0405), but this increase was not statistically significant at the second visit (1.19 fold, P = 0.3039) (Fig