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Despite that AMPs from different sources have different sequences and structures, they share several common points, including a net positive charge with a range of +2 to +13 (even to +14), hydrophobicity, and amphipathicity (Lv et al., 2014

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Among them, ORF3b, ORF6, ORF7a, and ORF8 accessory proteins are important type 1 interferon antagonists and have been associated with hijacking host-immune responses

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