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The purpose of this chapter is to provide the healthcare practitioner with an overview of the existing oral and injectable (non-insulin) pharmacological options available for the treatment of patients with T2DM

We employ variants of the peptides GLP-1 and exendin-4 to explore the interplay between helical propensity near the agonist N-terminus and the ability to bind to and activate the receptor

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But sizing the full, eventual impact of these drugs remains difficult, given a large number of unknowns/lingering unanswered questions, and the fast pace of change when it comes to continued clin

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