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Evidence Rating Level: 1 Study Rundown: The primary objective of the VESPER trial was to evaluate and compare the efficacy of two chemotherapy regimensdose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (dd-MVAC), and gemcitabine and cisplatin (GC)in patients with muscle-invasive bladder cancer undergoing radical cystectomy

This shift towards oral medications is expected to make effective weight loss treatments available to a broader population

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