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Physically, some individuals feel an immediate shift in their energy levels or a slight heaviness in the stomach as the medication begins to regulate blood sugar and digestion

It is also synthesized in the brainstem and acts as a neuromodulator within key regions involved in reward processing, stress regulation, and executive function

PLoS ONE (2017) 12:e0189060

Tier 2: lifestyle modifications that reduce reflux by 40 to 60% Beyond diet, specific behavioral changes significantly reduce reflux frequency and severity

Resistance training addresses both concerns simultaneously by applying mechanical load to both muscles and bones
