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If you crush the origami, it's still made of the same paper, but it has lost its form and, therefore, its purpose
Individual patient factors play a significant role
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Importantly, this relationship does not hold in all groups of patients including those with acute MI or other conditions which may cause discordance between right- and left-sided filling pressures like primary pulmonary hypertension, significant valvular disease, etc
N Engl J Med 361:4051
