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This waist circumference reduction is crucial because it indicates loss of visceral fat, the dangerous fat around your organs that contributes to metabolic disease

However, the FDA black-box warning about medullary thyroid carcinoma (MTC) and thyroid C-cell hyperplasia means semaglutide is contraindicated in patients with personal or family history of MTC or multiple endocrine neoplasia syndrome type 2

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Here are some stats: Pancreatitis is seen in about 0.2% of people in studies, which is similar to people not taking the drug, but its still a known risk so its taken seriously