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Labs are not routinely required unless clinically necessary

16 However, despite the encouraging findings from a recent meta-analysis, 13 there was an increase in adverse cardiovascular outcomes in patients with stable chronic heart failure treated with liraglutide versus placebo in a randomised trial, indicating that caution should be exercised in this situation

As a result, nausea and fullness are most pronounced during treatment initiation or dose escalation

The medication works through the same biological mechanisms at lower doses, but the magnitude and durability of metabolic outcomes at those levels have not been validated in randomized studies

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