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It increases the production of insulin, the hormone that lowers blood sugar levels, while also suppressing secretion of glucagon, the hormone that raises blood sugar levels

At study entry, 38% of the patients were taking sodium glucose cotransporter 2 (SGLT2) inhibitors or glucagon-like peptide-1 receptor agonists (GLP-1 RAs), medications for diabetes that have been shown to have beneficial effects on heart disease, including reducing heart failure, heart attacks and strokes

Of all glucose-lowering therapies, only sodiumglucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) consistently result in weight improvement

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It is one of the most widely discussed and actively studied peptide compounds in contemporary biomedical research literature