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Description
In summary, while L-cell depolarization is crucial for GLP-1 secretion, the role of the Kir6.2/SUR1 channel complex of the K ATP channels for mediating this process in vivo warrants clarification
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For instance, animal models have shown that GLP-1RAs administration reduces anxiety-like behaviors, potentially via neuromodulatory actions in brain regions such as the amygdala
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