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Description
Our findings offer the structural basis of ago-allosterism at GLP-1R and new knowledge to design better therapeutics
Today, drugs like Ozempic (semaglutide), Wegovy, and Mounjaro (tirzepatide) are being prescribed and demanded for obesity

Due to a short plasma half-life of native GLP-1, several synthesized GLP-1 receptor agonists (RAs) were developed for type 2 diabetes mellitus (DM) treatment
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