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Individuals with favorable genetic profiles may achieve robust weight loss on oral tirzepatide, while those with less-responsive variant combinations might benefit more from the higher bioavailability of injectable forms

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Liraglutide, semaglutide, and tirzepatide demonstrated significant weight loss (greater than 5%).This study highlights that newer anti-diabetic drugs, particularly GLP1-RA (glucagon-like peptide-1 receptor agonists) and Tirzepatide, are highly effective in promoting weight loss among patients with type 2 diabetes