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Its development represents a significant area of interest in obesity pharmacotherapy, particularly given the limitations of existing treatments in achieving sustained, substantial weight reduction in all patient groups

HFpEF is notoriously difficult to treat, and currently, only two drugs, the SGLT2 inhibitors dapagliflozin and empagliflozin, are FDA-approved to treat it

10.1016/j.addr.2018.07.009 93 ZhangH.WuT.WuY.PengY.WeiX.LuT.et al (2024)

(8) Obesity and bone have both a mechanical and metabolic relationship

For a beneficiary to qualify, their provider must submit a prior authorization request that attests the beneficiary is being prescribed the drug to reduce excess body weight and ongoing maintenance of weight reduction and that they fall into one of three categories related to BMI and other clinical diagnostic criteria (Figure 3)