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In conclusion, our study conducted within real-world clinical settings revealed a noteworthy association between the use of GLP-1 RAs, including Liraglutide and Semaglutide, and a heightened risk of psychiatric outcomes, encompassing depression, anxiety, and suicidal behaviour

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These variants do not determine outcome but may help contextualize why some patients tolerate therapy well while others experience persistent side effects

The good news is you can minimize muscle loss by following the guidelines in this guide: eat plenty of protein and engage in strength training [utswmed.org]

Cardio does some of this too, but not all of it and not always to the same degree