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Combined use is possible in appropriately screened patients, but requires baseline labs and ongoing provider monitoring

Fluids Barriers CNS 20 , 44 (2023)

Additionally, chronic treatment with GLP-1 RAs increases the abundance of anti-inflammatory microbial taxa (e.g., Bacteroidetes), which has been associated with improvements in both mood and glycemic control [94,95,99]

However, this data is crucial for calculating appropriate dosing for many drugs, especially weight-based medications, and for assessing clinical appropriateness

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