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Notably, these medications are not recommended for patients with severe gastroparesis or other significant gastrointestinal disorders, as stated in their FDA labeling

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J.et al (2018)

Clinical Efficacy Clinical trials demonstrate the potential of retatrutide to induce rapid weight loss

Side Effects: Common side effects include gastrointestinal issues such as nausea and diarrhea, especially at higher doses.These side effects were reversible and did not lead to severe complications