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In addition to the cholesterol lowering effects that result from inhibition of NPC1L1, its inhibition has been shown to have beneficial effects on components of the metabolic syndrome, such as obesity, insulin resistance, and fatty liver, in addition to atherosclerosis
doi: 10.1016/j.ebiom.2019.10.018 5 AdiguzelDCelik-OzenciC

Shiitake mushrooms are rich in polysaccharides (primarily glucans like lentinan), dietary fibers, proteins, vitamins, essential amino acids, sterols for flavoring, and other nutrients

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