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Description
This is confirmed by an increase in the production of proinflammatory cytokines IL-1, IL-6 and TNF-, through migration of the transcription factor NF-, the activating protein (AP-1) and cyclooxygenase 2 (COX2) activation [123]

Su funcin central en el metabolismo es transportar cidos grasos de cadena larga al interior de las mitocondrias, donde pueden ser oxidados para producir energa

In addition, adipokines derived from obese tissues (e.g., brown adipose tissues) can be delivered into the liver to cause hepatic inflammation [26]

Ann N Y Acad Sci 2004;1033:30-41

Nature 590 , 480485 (2021)
