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It facilitates cell migration to injury sites, promotes cell differentiation, supports actin-mediated tissue remodeling, and reduces scar tissue formation

This deficiency in NO production contributes to an increased susceptibility to EndMT, as NO typically helps maintain the endothelial phenotype and prevents excessive mesenchymal transformation (Tran et al., 2022

IJMS 22:11663

At the 15 mg dose, patients averaged 22% body weight reduction

All animal experimental protocols were approved by the Animal Ethics Committee, the Second Affiliated Hospital, School of Medicine, Zhejiang University (Approval number: 2023084)