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[6] Gallbladder, pancreas, and other class considerations Rapid or large-magnitude weight loss a defining feature of high-efficacy incretin therapy is a known risk factor for gallstones and cholecystitis, and GLP-1 agonists carry label cautions about pancreatitis and, based on rodent data, thyroid C-cell tumors (with a contraindication in personal/family history of medullary thyroid carcinoma or MEN 2)

Patients who require corticosteroids for other medical conditions face additional challenges in fracture healing, and this is one scenario where teriparatide may be particularly beneficial