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From a chemical point of view, these periods of ischemia followed by reperfusion are associated with the conversion of xanthine dehydrogenase into xanthine oxidase, which is a potent source of superoxide free radicals, thus increasing OS
In summary, while ERGO holds theoretical promise for cognitive frailty, overstated conclusions risk misguiding clinical translation
After 48 h, cells were incubated with 100 nM of TMRM T668 (ThermoFisher) and Hoechst 34589 (Sigma-Aldrich) in low glucose complete NB medium for 10 min at 37 C and 5% CO 2
[DOI] [PubMed] [Google Scholar] Bartesaghi S, Radi R
Lazel Gluta Pure C
