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It can be associated with: A sudden change in diet A diet with not enough fibre Not drinking enough fluid Loss of 'tone' of the bowel muscles in older people Pregnancy Medicines such as morphine or codeine Having to stay in bed for a long time Lack of exercise Whatever the cause, constipation can be uncomfortable

To inject hCG correctly, pinch the skin for a cutaneous injection or stretch it for an intramuscular one

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The interplay between GIP and GLP-1 creates synergistic effects that neither pathway achieves alone, which is why tirzepatide results exceeded those of semaglutide in head-to-head comparisons