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A recent study found increased intestinal permeability after treatment with additives, mainly with high sugar, in both Drosophila and a human cell co-culture dramatically reduced the IAP activity in both models [101]

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2.3.2.3 Ubiquitination The proteasome inhibitor bortezomib impedes the degradation of ubiquitinated P53 proteins, thereby stabilizing P53 and simulating a persistent stress state (76)

doi: 10.1016/j.neuron.2019.02.008 95 YeLBaeMCassillyCDJabbaSVThorpeDWMartinAMet al

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