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2.4 Effects of metabolism on immune cells in the TME Tumor-infiltrating immune cells have dual characteristics, some of which have the function of inhibiting tumor proliferation and metastasis, such as CD8+ cytotoxic T cells, natural killer (NK) cells, M1 macrophages, dendritic cells (DCs), etc., while others may be beneficial to tumor development, including Treg cells, M2 macrophages (78)
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Mantovani G, Isidori AM, Moretti C, Di Dato C, Greco E, Ciolli P et al (2019) Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the SERENA study, a randomized, double-blind, placebo-controlled trial
Costa ND, Stevenson PM
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