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1999) and in the use of CysGly by neurons (Dringen et al

Remarkably, JZ534 exhibited greater anticancer efficacy than curcumin at equivalent doses (410)

High glucose by itself was also shown to reduce GCLC transcription in mouse endothelial cells (Urata et al., 1996)

10.1038/nature11183 54 TaniguchiH.YamadaT.WangR.TanimuraK.AdachiY.NishiyamaA.et al (2019)

Opening at 2 mg weekly rather than 4 mg markedly softens early GI effects, and any higher weekly dose simply calls for more than one vial or a split across two sites
