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Interestingly, the addition of glutathione S-transferase (GST) to GSH leads to the conjugation process of toxic metals/xenobiotics and transports those metals into the vacuole (Figure 1)

These figures reveal that SMS is a significant material flow in fungal-agriculture systems, rather than a marginal by-product, underscoring its importance for valorisation and circular bioeconomy initiatives

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demonstrated that enzyme glutathione-s-transferase pi (GST-), which is present in keratinocytes and melanocytes, has a protective role against tumor progression, specifically sun exposure-associated melanoma cells
