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The metabolic pathways of anthraquinones include mainly hydrolysis, glucuronidation, sulfation, methylation/demethylation, hydroxylation/dehydroxylation, oxidation/reduction, acetylation, and esterification, among which hydrolysis, glucuronidation, and sulfation are dominant ( Anthraquinones laxatives inhibit the absorption of water and sodium in the colon by inhibiting the activities of Na + -K + -ATPase of colonic epithelial cells (Figure 2)

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