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Over-expression of PON1 in mice confers enhanced HDL anti-oxidative capacity, and PON1 itself prevents LDL oxidation in vitro (432)
TMAO inhibits the expression of sirtuin 3 (SIRT3) and the activity of superoxide dismutase 2 (SOD2), leading to the accumulation of mitochondrial ROS (mtROS)
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During that period, Tibbets was retained as a technical advisor on the Bikini Bomb Project
