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The disease is caused by the amplification of the CAG trinucleotide repeat in the first exon of the Huntingtin gene on chromosome 4 (Stoker et al., 2022)

Two primary tests measure the amount of B12 in blood (low in B12 deficiency): Total B12 test: measures total amount of B12 Active B12 test: measures amount of B12 that is available to the cells Two secondary tests measure function of B12 in the cell (raised in B12 deficiency): MMA: measures function of B12 in the mitochondria Homocysteine: measures function of B12 for methylation How does Vitamin B12 deficiency get diagnosed

Diggs C, Meyer WA, Langenberg P et al: Assessing urgency in interstitial cystitis/painful bladder syndrome

Polyglutamate directed coupling of bioactive peptides for the delivery of osteoinductive signals on allograft bone

B12 is also vital for the production of DNA, nerves and red blood cells in your body