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10.3389/fnagi.2023.1189809 114 HanganuA.BedettiC.DegrootC.Mejia-ConstainB.LafontaineA

10.2147/IJN.S444009 [DOI] [PMC free article] [PubMed] [Google Scholar] 136.Filannino FM, Panaro MA, Benameur T, Pizzolorusso I, Porro C

This sodium-independent system exchanges intracellular glutamate for extracellular cystine at a 1:1 ratio

Common lysosome-targeting groups include 4-(2-hydroxyethyl)morpholine, N,N-dimethylethylenediamine, and diethylene glycol methyl ether, 248 whose weak alkalinity makes them easy to aggregate in the acidic lysosomal environment and thus play a role in targeting lysosomes

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