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An first conservative cycle (4 weeks at moderate dose) may be followed by a longer or higher-dose cycle if response is suboptimal and tolerability is good

G6PD deficiency should be considered in neonates who develop hyperbilirubinemia within the first 24 hours of life, a history of jaundice in a sibling, bilirubin levels greater than the 95th percentile, and in Asian males

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