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EMA statement on ongoing review of GLP-1 receptor agonists (suicidal thoughts and self-harm signal)

The results of these studies suggest that opioids should be included among the therapeutic options for painful DSPN, provided that careful selection of patients unresponsive to standard treatments, regular monitoring, appropriate dose titration, and management of possible opioid-specific problems (analgesic misuse or addiction, tolerance, opioid-induced hyperalgesia) are ensured

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Safety profile : Are there potential adverse effects or interactions