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Cancer-cell metabolism studies NNMT is overexpressed in several cancer cell lines, and 5-Amino-1MQ has been used in vitro to characterise its role in tumour metabolism

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Specifically, it produces no IGF-1 elevation (avoiding proliferative concerns), no negative impact on glucose metabolism (avoiding diabetes risk), no fluid retention or edema, and no concerning patterns of joint pain that can occur with growth hormone

CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia