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The initiator of the pathophysiological process has not been elucidated yet, although acute gastrointestinal infections have been found to initiate the symptoms in a certain group of patients with IBS (post-infectious IBS) (81)

Preclinical and Clinical Evidence of CIPN: Major Antioxidants in Lines of Defense Melatonin Melatonin, which is synthesized by all kinds of cells, is principally secreted by the pineal gland and is known for maintaining aging, reproductive function, circadian rhythm and antioxidant activity [37]

No changes in cysteine concentrations or GCL enzyme activity

There are dynamic contact mechanisms between mitochondria and lysosomes
