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Antioxidative effects In cancer cells, overcoming oxidative stress is a critical step for tumor progression

The acidification step of samples for deproteinization must follow the reaction with NEM [8,10,14,20,34,35]

Look for "standardized extracts" to ensure you are getting the active compounds

The positive outcomes of agents like canakinumab and colchicine suggest that effective strategies must precisely target the key nodessuch as the IL-1 pathway or the NLRP3 inflammasomethat directly perpetuate the vicious cycle between oxidative stress and inflammation detailed in Section 2.4.1

However, a multicenter randomized controlled clinical trial showed that sorafenib only prolonged the median survival of patients with HCC by 10 months and lenvatinib by 15 months [13]