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[DOI] [PubMed] [Google Scholar] Nebert D
It shows estrogenic properties via binding to different estrogen receptors and has various biological effects in antioxidation and anti-aging (Spagnuolo et al., 2015
Notably, 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of oxidative DNA damage, is elevated in liver biopsy specimens of MASLD patients, and 31 P-MRS imaging has demonstrated ATP depletion consistent with mitochondrial dysfunction [101, 102]
Peroxynitrite Induces HO-1 Expression via PI3K/Akt-dependent Activation of NF-E2-Related Factor 2 in PC12 Cells
