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A: Some patients notice enhanced clarity or recall within 12 weeks

This represents approximately 28.6% of post-COVID IBS cases and 20% of general IBS cases

Additionally, p300, also termed CREB-binding protein, and steroid receptor coactivator-1 act as cofactors to form the HIF-1 transcriptional complex 38 (49)

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It is therefore clear that a strong state of oxidation (oxidative and nitro-oxidative stress) created by the plentiful, prolonged local production of ROS and RNS, is a decisive factor for the progression and chronicization of inflammation [60,61]
