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Signaling Pathways Affected by L-Carnitine Extensive research has focused on elucidating the signaling pathways associated with L-Carnitine, highlighting the involvement of Sirtuin 3 (SIRT3) [72] and nuclear factor erythroid 2-related factor 2 (Nrf2) [73]

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Funding: None.

Since LC is still used by the athletes [9, 10], the aim of this systematic review is to evaluate the effect of prolonged LC supplementation on metabolism/metabolic changes in healthy human subjects

Advancing preclinical models of psychiatric disorders with human brain organoid cultures