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(Hussain et al., 2019) developed an riboflavin crosslinked, high-density collagen (HDC) gel to deliver MSCs into AF defects in a safe and effective manner for annular repair in a sheep lumbar IVD injury model and improved outcomes in terms of DHI, Pfirrmann grade and T2-RT

Certain amino acids, like methionine, cysteine, tryptophan, and asparagine, are more prone to oxidation and hydrolysis

Use nightly until the product is finished

Dysregulation of Calcium Content Maintaining stable calcium levels through calcium pump activity and channels appears to be important to prevent cataract formation

PMID 35340552
