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Description
Serine and glycine can be mutually converted via hydroxymethyltransferases (cytosolic: SHMT1 and mitochondrial: SHMT2) [46]
Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a significant barrier to T-cell persistence in the TME

ALS mutations disrupt phase separation mediated by -helical structure in the TDP-43 low-complexity C-terminal domain

GDF15 Ameliorates liver fibrosis by metabolic reprogramming of macrophages to acquire anti-inflammatory properties

Biochem Pharmacol 2012;83(10):13191330
