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Strategies for improving the safety and RNAi efficacy of noncovalent peptide/siRNA nanocomplexes

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USP acceptable ranges: Benzyl Alcohol 0.72%1.08% | pH 4.07.0 Parrox Reconstitution Solution BA: 0.81% Pass | pH: 7.53 FAIL FAIL Lamda Water BA: 0.87% Pass | pH: 5.1 Pass PASS HydraTide Labs BA: 0.93% Pass | pH: 7.26 FAIL FAIL Awat Science BA: 0.81% Pass | pH: 8.8 FAIL FAIL BioVitalis Solutions BA: 0.83% Pass | pH: 6.92 Pass PASS JR Globals BA: 0.64% FAIL | pH: 6.7 Pass FAIL Regenix Research BA: 0.93% Pass | pH: 7.32 FAIL FAIL AaBaCa LLC BA: 0.87% Pass | pH: 8.69 FAIL FAIL LivWell Research Labs BA: 0.81% Pass | pH: 7.53 FAIL FAIL Quanta Nova Peptides BA: 0.72% Pass | pH: 7.87 FAIL FAIL Reconstitution Solution (Lot TE202601) BA: 0.61% FAIL | pH: 8.36 FAIL FAIL 9 out of 11 samples failed