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Cobamides are very efficient cofactors and coenzymes, and coupled with the fact that they are very stable entities means that, in general, only very small quantities of the nutrient are required within a cell

Physiol Rev 101:9951046

A pre-mixed reduced-glutathione solution would start converting to GSSG from the day it was manufactured, which forces a short shelf life and tight cold storage over the whole distribution chain

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and (iii) GABA stimulation of exosome-mediated signalling (Fig
