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The most promising contender against cellular damage caused by H 2 O 2 , 6-OHDA, and A1-42 was compound 5b, according to the results [133]
However, large molecules, hydrophilic compounds, and many therapeutic agents, such as antibodydrug conjugate (ADC), are excluded, limiting the ability of systemic treatment to reach the brain
Tranexamic acid is an active site inhibitor of urokinase plasminogen activator
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