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References 2016 The Author(s)

Pharmacol Ther 128:3760

Cureus 16 (2), e54855

Thus, targeting OXPHOS alone or in combination with other metabolic pathways could be an attractive therapeutic strategy to re-sensitise LSCs and AML blasts to conventional chemotherapeutic agents and improve AML patient outcomes

Currently, the field of cancer biology is transitioning from focusing solely on cells to a broader perspective that recognizes the interconnectedness between cancer cells and surrounding stromal cells