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The Mediterranean diet, with an intake of 2222 kcal/day, includes a balanced macronutrient profile of 37% fats, 18% proteins, and 18% carbohydrates, emphasizing high fiber, olive oil, vegetables, and fish for cardiovascular and anti-inflammatory benefits [165]

The diagnosis of metabolic syndrome requires three or more specific criteria, including elevated waist circumference, hypertriglyceridemia, reduced high-density lipoprotein cholesterol, hypertension, and elevated fasting blood glucose

[1] In the bloodstream, more than 95% of circulating IGF-1 is not free

& McShane, M

Subsequently, the interaction of dialkylimine with another molecule of -oxoaldehyde results in the formation of a Schiff base cation radical and the methylglyoxal radical (MGO )