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Persistent tiredness and fatigue Weakness or muscle fatigue A pale or slightly yellow tint to the skin A sore or inflamed tongue Pins and needles or numbness in the hands or feet Difficulty with memory or concentration Low mood or irritability Who Needs a Vitamin B12 Injection

Some dermatology case reports associate B12 injections with acneiform eruptions and rosacea flares

Intramuscular injections deliver B12 directly into muscle, which allows it to enter the bloodstream and bypass digestive absorption problems (NIH ODS)