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Description
Most patients respond well to a stepped-care approach: physical therapy and medication first, then targeted epidural injections, then minimally invasive options like the MILD procedure or laminectomy if conservative care is not enough
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30 Citicoline has improved brain energy metabolism and modulated the levels of acetylcholine, dopamine, and norepinephrine

These cytokines and chemokines induce further M1 polarization in a positive feedback loop (13, 2631)