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Perhaps most importantly, many peptides lack extensive long-term human studies

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Steroids plus other immunomodulators (azathioprine or cyclosporine) were received by 31% of patients and were associated with 2.5 times increased chance of SNL than usage of steroids alone (in 18.5%)

New Phytol 225:11661180 Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ (2009) Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis -aminobutyrate transaminase that utilizes both pyruvate and glyoxylate

Macrophage regulation of tumor responses to anticancer therapies